Most healthy cells rely on a complicated process to produce the fuel ATP. Ever wonder what the mitochondria in your cells do for. The mitochondria is important for understanding a cell’s normal state, as well as what happens when things go wrong. Also mitochondria is found that it relay’s on this transfer to make enough ATP to support normal cell metabolism. ATP is a nucleotide that performs many essential roles in the cell such as the mitochondria. It is the major energy currency of the cell, providing the energy for most of the energy-consuming activities of the cell.

Physiology at the Perelman School of Medicine, University of Pennsylvania, and colleagues discovered that fundamental control of ATP production is an ongoing shuttle of calcium to the mitochondria from another cell compartment.

The scientists from University of Pennsylvania were the ones who found that, mitochondria rely on this transfer to make enough ATP to support normal cell metabolism.  Most healthy cells rely on a complicated process to produce the fuel ATP. Also calcium channel in the inner membrane of mitochondria that lets calcium get into the mitochondrial matrix where it can do good things like promote ATP synthesis and healthy bioenergetics, or bad things, like mitochondrial-mediated cell death, apoptosis and necrosis. Which can deal with the function of the uniporter.

Because of these two papers, the uniporter is now recognized as a channel complex. Since the uniporter can be a therapeutic target is reperfusion injury, ischemic injury, and programmed cell death and its interaction are now targets for drug development.